Physon.Molecular · for drug discovery

Distribution-aware conformer generation

Compact diffusion model that produces 3D conformer ensembles for small molecules — beating RDKit's ETKDG on distribution shape (Bhattacharyya torsion-overlap up to 0.888) at a fraction of the sampling cost.

Built for high-throughput screening, docking prep, and ensemble docking pipelines. Every request compares Physon vs ETKDG in real time — see the deltas below.